I use different Newsbin configuration (.nbi) files that I select based upon my download source (.nzb files or header downloads). In the past, the default configuration used during Newsbin startup would be the same as the one used during the prior execution. However since I upgraded to ver. 6.72 this functionality has become inconsistent, and it may take several attempts (double clicking the .nbi file in the data folder), to change the default configuration.
It's not a big problem, but it has caught me by surprise a few times when invoking Newsbin via a .nzb link.