If you upgraded your OS since the last time the installer was run, or if you are running some windows registry cleaning software, like cclean, it may have removed the registry variable that tells the installer where to find your info. This can also happen if you change the Newsbin Data Folder location manually. You can recover from this by locating your original newsbin.nbi configuration file and launch Newsbin using that configuration. Search your hard drives for newsbin.nbi and look for one with a date from when Newsbin was last configured correctly. Then double-click on that file to launch Newsbin using those settings. If you need to change your data folder location, the procedure is here:
http://help.newsbin.com/index.php/V660- ... r_location